PCORnet, the National Patient-Centered Clinical Research Network, is an innovative initiative of the Patient-Centered Outcomes Research Institute (PCORI). The goal of PCORnet is to improve the nation's capacity to conduct clinical research by creating a large, highly representative network that directly involves patients in the development and execution of research.
PCORnet is made up of 33 partner networks - 13 Clinical Data Research Networks (CDRNs), based in healthcare systems such as hospitals, integrated delivery systems, and federally qualified health centers, and 20 Patient-Powered Research Networks (PPRNs), operated and governed by groups of patients and their partners focused on one or more specific conditions or communities, and interested in sharing health information and participating in research. Initially, these networks will be focused on more than 150 specific conditions and communities of interest. Over time, the intent is for PCORnet to serve as a platform for rigorous research on an even broader array of topics. The scientific expertise, large population size, and diversity of PCORnet make it a unique resource for both observational and interventional studies in these and other areas.
Richard Platt, MD, MSc, Adrian Hernandez, MD, MHS and Sharon Terry, MA are all co-Principal Investigators of the PCORnet Coordinating Center. The PCORnet Coordinating Center was selected and contracted by PCORI, and it is a partnership with PCORI and several organizations with expertise developing infrastructure to support clinical and patient-powered research networks' conduct of patient-centered comparative effectiveness research. These partners have collaborated to create and manage large, complex research networks using electronic health data to support clinical trials, comparative effectiveness research, health policy, and health services research.