Ann Chen Wu

Ann Chen Wu MD, MPH is an Associate Professor in the Department of Population Medicine at Harvard Medical School and Harvard Pilgrim Health Care Institute and the Director of the PRecisiOn Medicine Translational Research (PROMoTeR) Center. She is a pediatrician and health services researcher, and is the Director of the Center for Healthcare Research in Pediatrics (CHeRP). Dr. Wu is also leading the Age-Dependent Pharmacogenomics of Asthma Treatment (ADAPT) study; this research will link genetic variants to therapeutic responses with additional information from genomics and metabolomics to provide insight into the biologic pathways that may be activated in an age-dependent method.  This study will elucidate response to the two most commonly used medications for asthma, inhaled steroids and β2-agonists. She also leads development of the Precision Medicine Treatment (PreEMT) Model, a sophisticated computer model capable of simulating short- and long-term clinical benefits and estimating the cost-effectiveness of integrating different genome screening strategies into clinical care for healthy or high-risk newborns for a wide variety of heritable conditions. Her research interests are in health disparities, asthma, and pharmacogenetics.

After receiving her BS in Biology from the Massachusetts Institute of Technology and her MD from Harvard Medical School, Dr. Wu completed her pediatrics residency at Children's Hospital, Boston. She then spent two years in private practice in CT and completed a general pediatrics fellowship at Yale University School of Medicine. Prior to starting her faculty position at Department of Population Medicine, she was a Harvard Pediatric Health Services Fellow in the department and obtained an MPH from the Harvard School of Public Health. She practices general pediatrics at Children's Hospital Boston.

Dr. Wu is the lead investigator of the Age-Dependent Pharmacogenomics of Asthma Treatment (ADAPT) and co-lead on Genomics-based Technologies: Access and Reimbursement Issues. 



Assistant in Medicine, Department of Medicine, Division of General Pediatrics, Children’s Hospital, Boston, MA

Staff Assistant

Mikaela Batista

(617) 867-4580


Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement. (Pubmed Abstract)

Associate Professor

Work Phone
Mailing Address
Harvard Medical School
Department of Population Medicine
Landmark Center
401 Park Drive, Suite 401
Boston, MA 02215