Varicella-zoster virus infections in children infected with human immunodeficiency virus.

View Abstract

Primary varicella-zoster (VZ) infection in eight children with perinatally acquired human immunodeficiency virus infection tended to be severe, prolonged, complicated by bacterial infections and in one case fatal. Depletion of CD4-lymphocytes was associated with chronic and recurrent VZ infection. In some patients convalescent VZ antibody titers were low and did not correlate with recurrence of VZ lesions. Administration of acyclovir appeared to be beneficial in suppressing VZ in human immunodeficiency virus-infected children with primary or recurrent VZ infection.

Investigators
Abbreviation
Pediatr. Infect. Dis. J.
Publication Date
1999-11-30
Volume
8
Issue
9
Page Numbers
586-90
Pubmed ID
2797953
Medium
Print
Full Title
Varicella-zoster virus infections in children infected with human immunodeficiency virus.
Authors
Jura E, Chadwick EG, Josephs SH, Steinberg SP, Yogev R, Gershon AA, Krasinski KM, Borkowsky W