Tetracycline Resistance and Co-resistance in a Doxy-PEP-Eligible Population.

In infections in men eligible for doxycycline post-exposure prophylaxis (doxy-PEP), tetracycline non-susceptibility is more prevalent than in the overall population and is associated with resistance to trimethoprim-sulfamethoxazole and clindamycin. Doxy-PEP may select for multi-drug resistance, underscoring the importance of surveillance.