Comparing drug effectiveness at health plans: the ethics of cluster randomized trials.

View Abstract

"Cluster randomized trials," in which groups of patients are randomly assigned to different therapeutic interventions, provide a powerful way of evaluating drugs. CRTs have not been widely used, in good part because of concerns about whether patients must give informed consent to participate in them. A better understanding of how CRTs fit into clinical practice resolves the concerns.

Investigators
Abbreviation
Hastings Cent Rep
Publication Date
1999-11-30
Volume
38
Issue
5
Page Numbers
39-48
Pubmed ID
18947140
Medium
Print
Full Title
Comparing drug effectiveness at health plans: the ethics of cluster randomized trials.
Authors
Sabin JE, Mazor K, Meterko V, Goff SL, Platt R