Strain-relatedness of methicillin-resistant Staphylococcus aureus isolates recovered from patients with repeated infection.

View Abstract

Invasive disease following methicillin-resistant Staphylococcus aureus (MRSA) detection is common, regardless of whether initial detection involves colonization or infection. We assessed the genetic relatedness of isolates obtained > or =2 weeks apart representing either repeated infections or colonization-infection sets to determine if infections are likely to be caused by previously harbored strains. We found that MRSA infection following initial colonization or infection is caused by the same strain in most cases, suggesting that a single successful attempt at decolonization may prevent the majority of later infection.

Investigators
Abbreviation
Clin. Infect. Dis.
Publication Date
1999-11-30
Volume
46
Issue
8
Page Numbers
1241-7
Pubmed ID
18444862
Medium
Print
Full Title
Strain-relatedness of methicillin-resistant Staphylococcus aureus isolates recovered from patients with repeated infection.
Authors
Huang SS, Diekema DJ, Warren DK, Zuccotti G, Winokur PL, Tendolkar S, Boyken L, Datta R, Jones RM, Ward MA, Aubrey T, Onderdonk AB, Garcia C, Platt R