Therapeutics Projects

Determining the effectiveness of marketed drugs and vaccines, ensuring their safety, and improving the appropriateness of their use are longstanding, important societal challenges. Current activities focus on development of new knowledge, and of better local and national capabilities to perform collaborative research. We participate in several initiatives to develop distributed research networks to support therapeutics as well as other kinds of research and surveillance programs.


Please click on the links below to learn more about our recent Therapeutics Research


  • Sentinel is a national medical product monitoring system.


  • PopMedNet is a software platform that facilitates the creation, operation, and governance of distributed health data networks.

Research Program in Medication Use and Outcomes in Pregnancy (MEPREP)

  • Developing the infrastructure to enhance our ability to study the effects of medication exposure during pregnancy on the fetus by creating and maintaining linked data on mothers and infants

NIH Collaboratory

  • Health Care Systems Research Collaboratory

Patient-Centered Outcomes Research Network (PCORnet)

  • PCORnet, the National Patient-Centered Clinical Research Network, is designed to make it faster, easier, and less costly to conduct clinical research by harnessing the power of large amounts of health data and patient partnerships.

Privacy-protecting analytic and data-sharing methods

  • Develop, refine, and apply analytic methods that perform sophisticated statistical analyses without sharing of potentially identifiable patient-level information

The Biologics and Biosimilars Collective Intelligence Consortium (BBCIC)

  • A non-profit, scientific public service initiative that will monitor biosimilars and corresponding novel biologics for effectiveness and safety