Application of Life's Essential 8 to assess cardiovascular health during early childhood.

View Abstract

OBJECTIVES

Assess cardiovascular health (CVH) during early childhood using the American Heart Association's recently-updated construct, Life's Essential 8 (LE8); examine concordance in CVH status per LE8 vs. Life's Simple 7 (LS7); and identify perinatal correlates of high CVH per LE8.

METHODS

We applied LE8 and LS7 to data from 305 children aged 4-7 years in Denver, CO; estimated % low, moderate, high, and optimal CVH; assessed concordance in CVH status based on LE8 and LS7 using contingency tables; and used multivariable logistic regression to identify early-life correlates of high CVH per LE8.

RESULTS

Average age of children was 4.7±0.6 years; 44.6% were female. No participants had low or optimal CVH; 43.9% had high and 56.1% had moderate CVH per LE8, whereas 33.4% had high and 66.6% had moderate CVH per LS7. Twenty-two percent had high CVH based on both constructs. Correlates of high CVH were maternal prenatal diet quality (OR =1.90 [1.12, 3.21]) and child age (OR=1.58 [1.04. 2.42]).

CONCLUSIONS

LE8 yielded higher prevalence of high CVH than LS7 during early childhood, though there is modest concordance between the two constructs. Maternal diet is a potential modifiable target to optimize early-life CVH.

Investigators
Abbreviation
Ann Epidemiol
Publication Date
2023-02-09
Pubmed ID
36773850
Medium
Print-Electronic
Full Title
Application of Life's Essential 8 to assess cardiovascular health during early childhood.
Authors
Perng W, Aris IM, Slopen N, Younoszai N, Swanson V, Mueller NT, Sauder KA, Dabelea D