News

December 2018

"Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement" was published in the American Journal of Respiratory and Critical Care Medicine.

aw and ATS group

October 2018

Chris Lu and colleagues' publication "Implementing universal Lynch syndrome screening (IMPULSS): protocol for a multi-site study to identify strategies to implement, adapt, and sustain genomic medicine programs in different organizational contexts." is featured in BMC Health Services Research.

 

On October 26, 2018 Dr. Ann Wu presented "Asthma Pharmacogenetics from a Health Services Researcher's Point of View" at the Harvard School of Public Health's Program in Genetic Epidemiology and Statistical Genetics Seminar Series.

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ChERP and PROMoTeR are delighted to welcome Pamela McMahon, PhD to DPM! She has a PhD in Health Policy and Decision Science from Harvard and was an assistant professor in the Department of Radiology at MGH where she was the PI of the Cancer Intervention and Surveillance Modeling Network Lung Group.  Most recently, she was a Managing Scientist at Exponent, Inc. She will serve as Project Director of Ann Wu’s Precision Medicine Policy and Treatment (PreEMT) Model projects.  She is a person with many talents and is also an amazing artist!​​

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Ann Wu, Chris Lu and colleagues' publication "The Implementation Process for Pharmacogenomic Testing for Cancer-Targeted Therapies." is featured in the Journal of Personalized Medicine. 

 

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July 2018

Joanne Sordillo, Peter Kraft, Ann Wu and Maryam Asgari's publication "Quantifying the Polygenic Contribution to Cutaneous Squamous Cell Carcinoma Risk." is featured in the Journal of Investigative Dermatology. 

 

Maryam Asgari and colleagues published an article in Cancer Epidemiology, Biomarkers and Prevention entitled, "Common Mitochondrial Haplogroups and Cutaneous Squamous Cell Carcinoma Risk.

 

Joanne Sordillo and Emily Oken's publication "Relation of Prenatal Air Pollutant and Nutritional Exposures with Biomarkers of Allergic Disease in Adolescence." was featured in Scientific Reports.

 

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June 2018

Angel Mak, Esteban Burchard, Ann Wu and colleagues published an article in the American Journal of Respiratory and Critical Care Medicine entitled, "Whole genome sequencing of pharmacogenetic drug response in racially diverse children with asthma.

 

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May 2018

Maryam Asgari, Eric Jorgenson and colleagues published an article in Cancer Immunology, Immunotherapy entitled, "Genetic variants in the HLA class II region associated with risk of cutaneous squamous cell carcinoma.

 

Ann Wu, Emily Oken, Joanne Sordillo, Marie-France and colleagues published an article in Clinical and Experimental Allergy entitled, "Plasma Metabolite Profiles in Children with Current Asthma."

 

Christine Lu, Ann Wu and colleagues published an article in the Journal of Personalized Medicine entitled, "Insurance Coverage Policies for Pharmacogenomic and Multi-Gene Testing for Cancer."

 

Guest speaker, Dr. Eric Jorgenson, presented his talk "A View to Precision Medicine: Findings from the Research Program on Genes, Environment, and Health" on Monday May 7th. 

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March 2018

Christine Lu and colleagues published an article in Genetics in Medicine entitled, "Short-term costs of integrating whole-genome sequencing into primary care and cardiology settings: a pilot randomized trial." The paper has been featured by the STAT news

 

We are happy to welcome Michael Gooch, PhD to the PROMoTeR Center as a Programmer. He comes to us from UConn Health where he earned a PhD in Biomedical Science Genetics and Genome Sciences. Michael will be working with Ann Wu on her ADAPT and PreEMT studies. We are thrilled he has joined our team!  

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February 2018

On February 15th, the PROMoTeR Center had guest speaker, Dr. Blanca Himes, visit. She presented on "Biomedical Informatics Approaches to Study Asthma".

blanca himes feb 15

 

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December 2017

On Monday December 11th, the PROMoTeR Center had a seminar featuring Dr. Fred Tabung. He presented on "The Inflammatory and Insulinemic Potential of Diet and Risk of Cancer".

tabung invite

 

On Monday December 4th, the PROMoTeR Center had a seminar featuring Dr. Nilah Ioannidis. She presented on "Clinical interpretation of genetic variation: Statistical methods and application to cutaneous squamous cell carcinoma".

ioannidis talk

 

 

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November 2017

11/30 PROMoTeR group photo

PROMoTeR Center group presented their work to the Department

 

Christine Lu was invited to give a presentation, titled “A Model for Accelerating Evidence Generation for Genomic Technologies in the Context of a Learning Health Care System” at the "Implementing and Evaluating Genomic Screening Programs in Health Care Systems – A Workshop", National Academies of Sciences, Engineering and Medicine in Washington DC, November 1, 2017.

 

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October 2017

Christine Lu was invited as the Chair and a panelist of a session entitled, “Value based frameworks for precision medicine,” at the Evidence Pricing & Market Access World Congress, Philadelphia, PA, October 10-11, 2017.

 

Christine Lu was invited as part of a panel session “Putting the G in genome: Financial sustainability of genomic medicine” at the Festival of Genomics, Boston, MA, 3-4 October, 2017.

 

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September 2017

On Monday September 25th, the PROMoTeR Center will had a seminar featuring Dr. Sharon Lutz. She presented on "Approaches to Incorporate and Understand the Path from Gene to Disease."

lutz job talk invite

 

Congratulations to Ann Wu, MD MPH (Principal Investigator), Chris Lu, MSc PhD, and Natasha Stout, PhD, on receiving an R01 funded by the National Institute of Child, Health, and Human Development. In the grant, the Precision Medicine Treatment (PreEMT) Model, Dr. Wu and HPHC co-investigators, will develop a computer model capable of simulating short- and long-term clinical benefits and estimating the cost-effectiveness of integrating different genome screening strategies into clinical care for healthy or high-risk newborns for a wide variety of heritable conditions. With this model, they will synthesize the best available clinical, epidemiologic, and economic data on genetic variants present at birth for a wide variety of genetically-driven childhood conditions to project health outcomes, and provide a dynamic tool to evaluate evolving knowledge in the area of genomics and precision medicine in the United States over the next decade.

 

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August 2017

Christine Lu and colleagues published an article in Genetics in Medicine entitled, "A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system." The paper has been featured by the Centers for Disease Control and Prevention, Genomics and Health Impact Blog

 

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May 2017

Ann Wu with Maki Inada

Ann Wu organized a workshop to create "An Official Research Statement of the ATS and NHLBI: Current Status and Future Directions in Lung Precision Medicine Research." Dr. Wu is pictured with patient speaker, Maki Inada, a non-smoker, who beat non small cell lung cancer with the help of precision medicine.

 

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burchard visit

Esteban Burchard, MD MPH, advisor on President Obama's Precision Medicine Initiative working group, visited with the PROMoTeR Center.

 

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April 2017

AW at Radcliffe Workshop

Ann Wu participated in a Radcliffe Institute Seminar on Redesigning Health Systems for Precision Medicine.

 

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Peter Kraft Visit

Peter Kraft, Professor of Epidemiology at the Harvard School of Public Health, visited with members of the PROMoTeR Center.

 

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March 2017

 

PROMoTer March News HMS Course

Faculty from the PROMoTeR Center (Ann Wu, Christine Lu, and Maryam Asgari) attend the Harvard Medical School Leadership Development Course for Physicians and Scientists.

 

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Christine Lu was invited to give a presentation, titled “Genomic Medicine: Access, Coverage and Ethics” at the National Academies of Sciences, Engineering and Medicine (formerly Institute of Medicine) in March in Washington DC.