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December

Kurt Christensen, Emilie Zoltick, and colleagues article “Improved provider preparedness through an 8-part genetics and genomic education program” is published in Genetics in Medicine.

Mei-Sing Ong and colleagues article “Response to Editorial Accompanying STOP-JIA Articles by Ruperto, et al.” is published in Arthritis & Rheumatology.

Alon Peltz and colleagues article “The Association of the Childhood Opportunity Index on Pediatric Readmissions and Emergency Department Revisits” is published in Academic Pediatrics.

Joanne Sordillo, Sharon Lutz, Ann Wu, and colleagues article “Pharmaco-Metabolomics of Inhaled Corticosteroid Response in Individuals with Asthma” is published Journal of Personalized Medicine.

Special thanks to Dr. Hadley Stevens Smith, PhD, MPSA for presenting at our December CHeRP seminar. Dr. Smith presented “Patient-centered approaches to evaluation of genomic medicine: Bridging health economics and the ethical, legal, and social implications of genomics”.

November

Davene Wright and colleagues’ article “Impact of the COVID-19 Pandemic on Cardiovascular Science: Anticipating Problems and Potential Solutions: A Presidential Advisory From the American Heart Association” is published in Circulation.

Ann Wu, Pamela McMahon, and colleagues’ article “Characteristics of new adult users of mepolizumab with asthma in the USA” is published in BMJ Open Respiratory Research.

Davene Wright and colleagues’ article “Intergenerational Decision Making: The Role of Family Relationships in Medical Decision Making” is published in MDM Policy & Practice.

Alon Peltz presented at the Massachusetts Association of Health Plans 2021 Virtual Annual Conference. Dr. Peltz presented, "Preliminary Findings on Wi-Fi Telehealth Study: Advancing Telehealth Equity."

Natalia Kunst, PhD presented at the November CHeRP/HPI Seminar. Dr. Kunst presented “Improving Medical Decision Making: Evidence and Uncertainty Considerations”

CHeRP welcome a new staff member in November:

Georgia Okolita joined as a new Administrative Specialist for the group!

October

Kurt Christensen, Ann Wu, and colleagues’ article “Estimated Cost-effectiveness of Genetic Testing in Siblings of Newborns With Cancer Susceptibility Gene Variants” is published in JAMA Network Open.

The paper was also featured in NIH/NICHD News Release “Genetic testing of the siblings of newborns with cancer genes could reduce rare pediatric cancer deaths by half, NIH-funded analysis suggests.” It was also featured in genomeweb's “Analysis Finds Sibling Cascade Testing Could Be Cost Effective in Pediatric Cancer.”

Kurt Christensen and colleagues’ article “Do research participants share genomic screening results with family members?” is published in Journal of Genetic Counseling.

Sharon Lutz and colleagues’ article “Associations between an integrated component of maternal glycemic regulation in pregnancy and cord blood DNA methylation” is published in Epigenomics.

Joanne Sordillo and colleagues’ article “Association of Mode of Obstetric Delivery With Child and Adolescent Body Composition” is published in JAMA Network Open.

Cheers to Davene Wright, who was recognized at the Harvard Medical School Faculty Fellowship Recognition Reception through the Office of Diversity Inclusion and Community Partnership (DICP).

September

Ann Wu, Alison Galbraith, and colleagues’ paper “Out-of-Pocket Spending for Asthma-Related Care Among Commercially Insured Patients, 2004-2016” is published in The Journal of Allergy and Clinical Immunology: In Practice.

Katherine Yih and colleagues’ paper “Surveillance for Adverse Events After COVID-19 mRNA Vaccination” is published in JAMA.

Alon Peltz, Alison Galbraith, and colleagues’ paper “In New England, Partisan Differences In ACA Marketplace Participation And Potential Financial Harm” is published in Health Affairs.

Joanne Sordillo, Sharon Lutz, Ann Wu, and colleagues’ article “A polygenic risk score for asthma in a large racially diverse population” is published in Clinical & Experimental Allergy.

Sharon Lutz and colleagues’ article “Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease” is published in Journal of Cachexia, Sarcopenia and Muscle.

Alon Peltz presented at a department Brown Bag Seminar in September. Alon presented “Building a Distributed Data and Research Network to Study Telehealth Equity: Early Insights from the WIFI study”.

Special shout out to CHeRP Members Jessica LeBlanc, Mikaela Batista, and Natalia Kunst who all participated in the Red Sox Foundation Volunteer event as a part of volunteer week 2021.

CHeRP welcomed two new members in September:

Madison Hickingbotham - Research Assistant

Claire Abraham - Research Fellow

August

Kurt Christensen and colleagues’ article “Effects of participation in a U.S. trial of newborn genomic sequencing on parents at risk for depression” is published in Journal of Genetic Counseling.

Sharon Lutz and colleagues’ article “Early-pregnancy maternal body mass index is associated with common DNA methylation markers in cord blood and placenta: a paired-tissue epigenome-wide association study” is published in Epigenetics.

Kurt Christensen and colleagues’ article “Psychosocial Effect of Newborn Genomic Sequencing on Families in the BabySeq Project: A Randomized Clinical Trial” is published in JAMA Pediatrics.

Ann Wu and colleagues’ article “Validation of the Association of Oral Corticosteroid Bursts With Adverse Events in Children-Reply” is published in JAMA Pediatrics.

Kurt Christensen and colleagues’ article “Behavioral and psychological impact of genome sequencing: a pilot randomized trial of primary care and cardiology patients” is published in NPJ Genomic Medicine.

July

Sharon Lutz and colleagues' article “Seasonal Variation in miR-328-3p and let-7d-3p Are Associated With Seasonal Allergies and Asthma Symptoms in Children” is published in Allergy, Asthma & Immunology Research.

Ann Wu and colleagues' article “Creative Approaches for Assessing Long-term Outcomes in Children” is published in Pediatrics.

Davene Wright and colleagues' article “Obesity and Health-Related Quality of Life in Children Hospitalized for Acute Respiratory Illness” is published in Hospital Pediatrics.

Katherine Yih and colleagues’ article “COVID-19 Vaccination Coverage Among Insured Persons Aged ≥16 Years, by Race/Ethnicity and Other Selected Characteristics — Eight Integrated Health Care Organizations, United States, December 14, 2020–May 15, 2021” is published in CDC Morbidity" and Mortality Weekly Report (MMWR).

Emilie Zoltick and colleagues’ article “Sugar-sweetened beverage, artificially sweetened beverage and sugar intake and colorectal cancer survival” is published in British Journal of Cancer.

Davene Wright and colleagues’ article “The clock is ticking: Parental stress around emerging adulthood for adolescents with type 1 diabetes” is published in Journal of Pediatric Nursing.

Alon Peltz, MD, MBA, MHS presented at CHeRP’s July Seminar. Dr. Peltz presented Equity in telehealth use during the COVID-19 pandemic: early insights from an all-payer cohort”.

June

Lauren Galbraith, Kurt Christensen, and colleagues’ article “Primary care providers’ responses to unsolicited Lynch syndrome secondary findings of varying clinical significance” is published in Genetics in Medicine.

Sharon Lutz and colleagues’ article “Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain” is published in Genetic Epidemiology.

CHeRP welcomed three new staff members this month:

Amy Han, MPH, Project Manager

Haley Sullivan, Summer PhD Student

Natalia Kunst, Research Fellow

Davene Wright’s NIH R03 grant proposal “Parent-Perceived Important Topics for Childhood Obesity (PPITCH)” was funded! Congratulations, Davene!

Davene Wright presented at a DPM Brown Bag Seminar in June. Davene presented, “The Audacity of Hope: Conducting a clinic-based RCT with adolescents during a pandemic”.

CHeRP hosted Dr. Sadiqa Kendi, MD, FAAP, CPST Division Chief of Pediatric Emergency Medicine from Boston Medical Center as our June CHeRP Seminar Speaker. Dr. Kendi presented “Time for your Check-Up! Feasibility and Acceptability of Quarterly Infant Car Seat Checks”.

Dr. Sadiqa Kendi presented the June CHeRP seminar.

May

Joanne Sordillo, Sharon Lutz, Ann Wu, and colleagues’ article “Pharmacogenetic Polygenic Risk Score for Bronchodilator Response in Children and Adolescents with Asthma: Proof-of-Concept” is published in Journal of Personalized Medicine.

Published in Precision Oncology News, “Researchers Weigh Benefits, Costs of Screening Newborns for Cancer Risk Mutations” references a Genetics in Medicine article showcasing results from the Precision Medicine Policy and Treatment (PreEMPT) Model led by CHeRP Director, Ann Wu.

Alison Galbraith, Ann Wu, Alon Peltz, and colleagues’ article “Controller Medication Use and Exacerbations for Children and Adults With Asthma in High-Deductible Health Plans” is published in JAMA Pediatrics.

Sharon Lutz, Ann Wu, and colleagues’ article “Caution against examining the role of reverse causality in Mendelian Randomization” is published in Genetic Epidemiology.

Davene Wright and Mikaela Batista presented at the department’s Brown Bag Seminar in May. Davene and Mikaela presented “Abstract Concepts: Using Visual Abstracts and Social Media to Promote Your Research”.

Kurt Christensen, PhD presented at this month's CHeRP Seminar. Dr. Christensen presented “The costs of population genetic screening”.

Congratulations to CHeRP Director Ann Wu, who is the recipient of this year’s DPM Gordon Moore Award for Excellence in Mentoring!

April

Kurt Christensen, Lauren Galbraith, Jessica LeBlanc, Emilie Zoltick and colleagues’ article “Precision Population Medicine in Primary Care: The Sanford Chip Experience is published in Frontiers in Genetics.

Alon Peltz and colleagues’ article “Racial and Ethnic Differences in Managed Care Enrollment Among US Children” is published in JAMA Network Open.

Katherine Yih and colleagues’ article “A COVID‐19‐ready public health surveillance system: The FDA's Sentinel System” is published in Pharmacoepidemiology and Drug Safety.

Sharon Lutz and colleagues’ article “Multi‐omics analyses implicate EARS2 in the pathogenesis of atopic dermatitis” is published in Allergy.

Joanne Sordillo and colleagues’ article “DNA methylation architecture of the ACE2 gene in nasal cells of children” is published in Scientific Reports.

Ann Wu and colleagues’ article “Association of Oral Corticosteroid Bursts With Severe Adverse Events in Children” is published in JAMA Pediatrics.

Sharon Lutz and colleagues’ article “A fast and efficient smoothing approach to Lasso regression and an application in statistical genetics: polygenic risk scores for chronic obstructive pulmonary disease (COPD)” is published in Statistics and Computing.

Alon Peltz and colleagues’ article “Association of Clinical Guidelines and Decision Support with CT use in Pediatric Mild Traumatic Brain Injury” is published in The Journal of Pediatrics.

Joanne Sordillo and colleagues’ article “Residential PM 2.5 exposure and the nasal methylome in children” is published in Environment International.

Kurt Christensen presented “Population Genetic Screening: expectations and process outcomes” at a recent DPM Brown Bag Seminar.

March

Director Ann Wu was one of the theme coordinators for the March 2021 issue of The Journal of Allergy and Clinical Immunology: In Practice.

Ann Wu, MD, MPH, was a theme coordinator for this issue of JACI: In Practice.

Director Ann Wu and colleagues’ article “Biologic Therapy in Allergy Practice: A New Era in Treatment Has Begun” is published in The Journal of Allergy and Clinical Immunology: In Practice.

Alon Peltz, Alison Galbraith, and colleagues’ article “Understanding Consumer Experiences and Insurance Outcomes Following Plan Disenrollment in the Nongroup Insurance Market” is published in Medical Care Research and Review.

Ann Wu, Kurt Christensen, Pamela McMahon, and colleagues’ article “Universal newborn genetic screening for pediatric cancer predisposition syndromes: model-based insights” is published in Genetics in Medicine.

CHeRP hosted Dr. Jean L. Raphael, MD, MPH from Baylor College of Medicine and Texas Children’s Hospital as CHeRP’s visiting professor for our March CHeRP Seminar. Dr. Raphael presented “Addressing Social Determinants of Health through Medicaid Policy Research”.

February

Alon Peltz and colleagues’ article “Racial and Ethnic Differences in Emergency Department Diagnostic Imaging at US Children’s Hospitals, 2016-2019” is published in JAMA Network Open.

Alison Galbraith, Ann Wu, Alon Peltz, and colleagues’ article “Association of Controller Use and Exacerbations for High-Deductible Plan Enrollees with and without Family Members with Asthma” is published in Annals of American Thoracic Society.

Katherine Yih and colleagues’ article “A Broad Safety Assessment of the 9-Valent Human Papillomavirus Vaccine” is published in American Journal of Epidemiology.

Davene Wright and colleagues’ article “Applied Methods for Estimating Transition Probabilities from Electronic Health Record Data” is published in Medical Decision Making.

Ryan Walsh, Kirsten Voorhies, Joanne Sordillo, Ann Wu, Sharon Lutz, and colleagues’ article “The Role of SNP Interactions When Determining Independence of Novel Signals in Genetic Association Studies—An Application to ARG1 and Bronchodilator Response” is published in Journal of Personalized Medicine.

CHeRP hosted Dr. Gilbert Gonzales, PhD, MHA from Vanderbilt University for our February CHeRP Seminar. Dr. Gonzales presented “Mental Health Needs Among LGBTQ College Students During COVID-19”.

January

Member Alison Galbraith and colleagues’ paper “Children’s Coverage Vulnerabilities With Loss of a Parent’s Employer-Sponsored Insurance” is published in AAP Pediatrics.

Director Ann Wu and colleagues’ paper "Pharmacogenetics of inhaled corticosteroids and exacerbation risk in adults with asthma” is published in Clinical & Experimental Allergy.

Members Kirsten Voorhies, Joanne Sordillo, Sharon Lutz, Ann Wu and colleagues’ paper “Age by Single Nucleotide Polymorphism Interactions on Bronchodilator Response in Asthmatics” is published in Journal of Personalized Medicine.

Congratulations to faculty member Alon Peltz for his K23 Award from NHLBI entitled “Sociomarker to Predict Asthma Control and Emergency Room visits (SPACER)”!

Congratulations to faculty member Alon Peltz for his new award with Massachusetts Association of Health Plans: "Web-based medical care and the health Inequities Formed during the Covid-19 Pandemic (The WIFI Study)".

Congratulations to faculty member Alon Peltz on receiving the 2021 Ebert Fellowship! Given annually in memory of Robert H. Ebert, founder of Harvard Community Health Plan and former Dean of Harvard Medical School, the Ebert Fellowship is part of the Harvard Medical School Eleanor and Miles Shore Faculty Development Awards.

CHeRP hosted Dr. Nia Heard-Garris, MD, MSc, FAAP from Lurie Children’s Hospital/Northwestern University Feinberg School of Medicine for our January CHeRP Seminar. Dr. Heard-Garris presented “Using the evidence to understand ACEs (Adverse Childhood Experiences), equity, and our voice”.