Biostatistics Publications: Pre-2015

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Publications Pre-2015

Young JG, Eskenazi B, Gladstone EA, Bradman A, Pedersen L, Johnson C, Barr DB, Furlong CE, and Holland NT.  Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonates.  Neurotoxicology.  2005;26(2):199-209.

Eskenazi B, Warner M, Samuels S, Young J, Gerthoux P, Needham L, Patterson D, Castorina R, Olive D, Gavoni N,  Vercellini P, and Mocarelli P. Serum dioxin concentrations and risk of uterine fibroids in the Seveso Women's Health Study. American Journal of Epidemiology. 2007;166(1):79-87.

Young JG, Jewell NP, and Samuels S. Regression analysis of a disease onset distribution using diagnosis data. Biometrics. 2008;64(1):20-8. PMCID: PMC2453193

Young JG, Hernán MA, Picciotto S, and Robins JM. Relation between three classes of structural models for the effect of a time-varying exposure on survival. Lifetime Data Analysis. 2010;16(1):71-8  PMCID: PMC3635680

Young JG, Cain LE, Robins JM, O'Reilly EJ, and Hernán MA. Comparative effectiveness of dynamic treatment regimes: an application of the parametric g-formula. Statistics in Biosciences. 2011;3(1):119-43.  PMCID: PMC3769803

Picciotto S, Hernán MA, Page JH, Young JG, and Robins JM. Structural nested cumulative failure time models to estimate the effects of interventions. Journal of the American Statistical Association. 2012;107(499):886-900.  PMCID: PMC3860902

Westreich D, Cole SR, Young JG, Palella F, Tien PC, Kingsley L, Gange SJ, and Hernán MA. The parametric g-formula to estimate the effect of highly active antiretroviral therapy on incident AIDS or death. Statistics in Medicine. 2012;31(18):2000-9.  PMCID: PMC3641816

Lajous M, Willett WC, Robins JM, Young JG, Rimm E, Mozaffarian D, and Hernán MA. Changes in fish consumption in midlife and the risk of coronary heart disease in men and women. American Journal of Epidemiology. 2013;178(3):382-91.  PMCID: PMC3727335

Young JG and Tchetgen Tchetgen EJ.  Simulation from a known Cox MSM using standard parametric models for the g-formula. Statistics in Medicine. 2014; 33(6):1001-14.  PMCID: PMC3947915

Young JG, Hernán MA, and Robins JM.  Identification, estimation and approximation of risk under interventions that depend on the natural value of treatment using observational data. Epidemiologic Methods. 2014; 3(1): 1-19.  PMCID: PMC4387917

Jacobson J, Lederman M, Spritzler J, Valdez H, Tebas P, Skowron G,  Wang R, Jackson JB, Fox L, and Gilbert M, for the ACTG 5041 Team. Granulocyte-Macrophage Colony-Stimulating Factor induces modest increases in plasma HIV RNA and CD4 lymphocyte counts in patients with uncontrolled HIV infection. The Journal of Infectious Diseases 2003; 188:1804-1814.

Malhotra U, Bosch RJ, Chan E, Wang R, Fischl MA, Collier AC, and McElrath JM.  Association of T cell proliferative responses and phenotype with virus control in chronic progressive HIV-1 disease.  The Journal of Infectious Disease 2004; 189:515-5

Malhotra U, Bosch RJ, Wang R, Collier A, McElrath MJ. Effect of adjunct Hydroxyurea on helper T cell immunity in HIV-1-Infected patients with virologic suppression. AIDS Research and Human Retroviruses 2004; 20: 807-12.

Jacobson JM, Bucy PR, Spritzler J, Saag MS, Eron J, Coombs RW, Wang R, Fox L, Johnson VA, Cu-Uvin S,  Cohn S, Mildvan D, O’Neil D, Janik J, Purdue L, O’Connor DK, Vita CD, Frank I and the NIAID -- ACTG 5068 Protocol Team.   Evidence that intermittent structured treatment interruption (STI), but not immunization with ALVAC-HIV vCP1452, promotes host control of HIV replication: the results of AIDS Clinical Trials Group 5068.  The Journal of Infectious Diseases 2006; 194: 623-32.

Benson CA, Vaida F, Havlir DV, Downey GF, Lederman MM, Gulick RM, Glesby MJ, Wantman M, Bixby CJ, Rinehart AR, Snyder S, Wang R, Patel S,  and Mellors JW, the ACTG A5086 Study Team. A randomized trial of treatment interruption followed by optimized antiretroviral therapy for persons with drug resistant HIV: 48-week virologic results of ACTG A5086. The Journal of Infectious Diseases 2006; 194: 1309-18.

Bosch RJ, Wang R, Vaida F, Lederman MM, Albrecht MA, and the AIDS Clinical Trial Group 364 Study Team. Changes in the slope of the CD4 cell count increase after initiation of potent antiretroviral treatment. The Journal of Acquired Immune Deficiency Syndromes (JAIDS) 2006; 43: 433-5.

Evans SR, Wang R, Yeh T, Anderson J, Haija R, Mcbratney-Owen PM, Peeples L, Sinha S, Xanthakis V, Rajicic N, Zhang J. Evaluation of distance learning in an `Introduction to Biostatistics' class: a case study. Statistical Education Research Journal 2007; 6(2): 59-77.

Wang R, Lagakos SW, Ware JH, Hunter DJ, Drazen JM. Statistics in medicine - reporting of subgroup analyses in clinical trials. New England Journal of Medicine 2007; 357:2189-94. [Also included in: Medical Use of Statistics, Bailar JC and Hoaglin DC ed., Wiley , 343-352, 2009.]

Novitsky V, Wang R, Kebaabetswe L, Greenwald J, Rossenkhan R, Moyo S, Musonda R, Woldegabriel E, Lagakos SW, and Essex M.  Better control of early viral replication is associated with slower rate of elicited antiviral antibodies in the detuned EIA during primary HIV-1C infection. The Journal of Acquired Immune Deficiency Syndromes (JAIDS) 2009; 52: 265-272.

Souglakos J, Philips J, Wang R, Marwah S, Silver M, Tzardi M, Silver J, Ogino S, Hooshmand S, Kwak E, Freed E, Meyerhardt JA, Saridaki Z, Georgoulias V, Finkelstein D, Fuchs CS, Kulke MH, and Shivdasani RA. Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. British Journal of Cancer 2009; 101,465-472.

Wang R, Lagakos SW. Inference after variable selection using restricted permutation methods. Canadian Journal of Statistics, 2009; 37(4), 625-644.

Wang R, Lagakos SW. On the use of adjusted cross-sectional estimators of HIV incidence. The Journal of Acquired Immune Deficiency Syndromes (JAIDS), 2009; 52(5):538-47.

Novitsky V, Wang R, Margolin L, Baca J, Kebaabetswe L, Rossenkhan R, Bonney C, Herzig M, Nkwe D, Moyo S, Musonda R,  Woldegabriel E, van Widenfelt E, Makhema J, Lagakos S, and Essex M. Timing constraints of in Vivo gag mutations during primary HIV-1 subtype C infection. PLoS One. 2009 Nov 5; 4(11):e7727.

Wang R, Tian L, Cai T, Wei LJ. Nonparametric inference procedure for percentiles of the random effects distribution in meta analysis. The Annals of Applied Statistics, 2010; 4(1): 520-532.

Novitsky V, Wang R, Lagakos S, and Essex M. HIV-1 subtype C phylodynamics in the global epidemic. Viruses 2010; 2(1):33-54.

Rothenberg SM, Mohapatra G, Rivera MN, Winokur D, Nitta M, Sadow PM, Sooriyakumar G, Brannigan BW, Ulman MJ, Perera RM, Wang R, Ma X, Erlander M, Rocco JW, Cohen E, Louis DN, Settleman J, Haber DA. A genome-wide screen for microdeletions reveals disruption of polarity gene components in diverse human cancers. Cancer Research, 2010; 70(6): 2158-64.

Novitsky V, Wang R, Bussmann H, Lockman S, Baum M, Shapiro R, Thior I, Wester C, Wester CW, Ogwu A, Asmelash A, Musonda R, Moyo S, van Widenfelt E, Mine M, Moffat C, Mmalane M, Makhema J, Marlink R, Gilbert P, Seage GR, De Gruttola V, and Essex M. HIV-1 subtype C infected individuals maintaining high viral load as a potential target for the “Test-and-Treat” approach to reduce HIV transmission. PLoS One, 2010; 5(4): e10148.

Novitsky V, Wang R, Margolin L, Baca J, Moyo S, Musonda R, Essex M. Dynamics and timing of in Vivo mutations at Gag residue 242 during primary HIV-1 subtype infection. Virology, 2010; 403(1): 37-46.   

Finkelstein DM, Wang R, Ficociello LH, Schoenfeld DA. A score test for association of a longitudinal marker and an event with missing data. Biometrics, 2010; 66(3): 726-732.

Wang R, Lagakos SW, Gray BJ. Testing and interval estimation of 2-sample survival comparisons with small sizes and unequal censoring. Biostatistics, 2010; 11(4): 676-692.

Wang R, Lagakos SW. Augmented cross-sectional prevalence testing for estimating HIV incidence. Biometrics, 2010; 66(3): 864-874.

Tian L, Wang R, Cai T, Wei LJ. The highest confidence density region and its applications to joint inferences about constrained parameters. Biometrics, 2011, 67(2): 604-610.

Abi-Raad R, Boutrus R, Wang R, Niemierko A, Macdonald S, Smith B, Taghian AG. Patterns and risk factors of locoregional recurrence in T1-T2 node negative breast cancer patients treated with mastectomy: implications for postmastectomy radiotherapy. International Journal of Radiation Oncology, Biology, Physics, 2011, 81(3):e151-7.

Haun JB, Castro CM, Wang R, Pruzinsky V, Marinelli BS, Lee H, Weissleder R.  Micro-NMR for rapid molecular analysis of human cancer cells. Science Translational Medicine, 2011, 3, p.71ra16.

Novitsky V, Wang R, Margolin L, Baca J, Rossenkhan R, Moyo S, van Widenfelt E, Essex M. Transmission of single and multiple viral variants in primary HIV-1 subtype C infection. PLoS One, 2011, 6(20): e16714.

Novitsky V, Ndung’u T, Wang R, Bussmann H, Chonco F, Makhema J, DeGruttola V, Walker BD, Essex M. Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection. AIDS, 2011, 25(12): 1515-1522.

Novitsky V, Wang R, Baca J, Margolin L, McLane MF, Moyo S, van Widenfelt E, Makhema JM, Essex M. Evolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection. Virology 2011, 421(2): 119-28.

Claggett B, Lagakos SW, Wang R. Augmented cross-sectional studies with abbreviated follow-up for estimating HIV incidence. Biometrics 2012, 68(1): 62-74.   (Doctoral student dissertation paper)

Wang R, Bosch R, Benson C, Lederman M. Drug resistant virus has reduced ability to induce immune activation.  The Journal of Acquired Immune Deficiency Syndromes (JAIDS), 2012; 61(4): e60-e63.

Wang R, Ware JH.  Detecting moderator effects using subgroup analyses. Prevention Science 2013, 14(2): 111-120.

Billings ME, Rosen CL, Wang R, Auckley D, Benca R, Foldvary-Schaefer N, Iber C, Zee P, Redline S, Kapur VK. Is the relationship between race and CPAP adherence mediated by sleep duration? Sleep, 2013; 36(2):221-7.

Novitsky V, Wang R, Rossenkhan R, Moyo S, Essex M. Intra-host evolutionary rates in HIV-1C env and gag during primary infection. Infection, Genetics, and Evolution, 2013; 19:361-8.

Wang R, Weng J, Moyo S, Pain D, Barr CD, Maruapua D, Mongwato D, Makhema J, Novitsky V, Essex M. Effect of short-course antenatal Zidovudine and single-dose Nevaripine on the BED capture enzyme immunoassay levels in HIV-1 subtype C infection. AIDS Research and Human Retroviruses, 2013, 29(6): 901-6.

Novitsky V, Bussmann H, Logan A, Moyo S, van Widenfelt E, Okui L, Mmalane M, Baca J, Buck L, Phillips E, Tim D, McLane MF, Lei Q, Wang R, Makhema J, Lockman S, De Gruttola V, Essex M. Phylogenetic relatedness of circulating HIV-1C variants in Mochudi, Botswana. PLoS One, 2013; 8(12):e80589. 

Weinstock T, Rosen CL, Marcus CL, Garetz S, Mitchell RB, Amin R, Paruthi S, Katz E, Arens R, Weng J, Ross K, Chervin RD, Ellenberg S, Wang R, Redline S. Predictors of obstructive sleep apnea severity in adenotonsillectomy candidates. Sleep, 2014; 37(2):261-269. 

Moyo S, LeCuyer T, Wang R, Gaseitsiwe S, Weng J, Musonda R, Bussmann H, Mine M, Engelbrecht S, Makhema J, Marlink R, Baum MK, Novitsky V, Essex M. Evaluation of the false recent classification rates of multi-assay algorithms in estimating HIV-1 subtype C incidence. AIDS Research and Human Retroviruses, 2014; 30(1): 29-36.

Carnegie NB, Wang R, Novitsky V, De Gruttola V. Linkage of viral sequences among HIV-infected village residents in Botswana: estimation of linkage rates in the presence of missing data. PLOS Computational Biology, 2014; 10(1):e1003430. 

Wang R, Goyal R, Lei Q, Essex M, De Gruttola V. Sample size considerations in the design of cluster randomized trials of combination HIV prevention. Clinical Trials, 2014; 11:309-318. 

Gleason K, Shin D, Rueschman M, Weinstock T, Wang R, Ware JH, Mittleman MA, Redline S. Recruitment yields in a randomized controlled study of cardiovascular disease reduction in sleep apnea: impact of mode and source of recruitment.  Sleep, 2014; 37(12):2035-8.

Hicks MH, Li Z (2003) Partner Violence and Major Depression in women: A Community Study of Chinese Americans, Journal of Nervous and Mental Diseases, 2003 Nov; 191(11): 722-9.

Jha AK, Li Z, Orav EJ, Epstein AM. Care in U.S. hospitals – The Hospital Quality Alliance program. N Engl J Med, 2005 Jul 21; 353(3):265-74.

Jha AK, Fisher ES, Li Z, Orav EJ, Epstein AM. Racial trends in the use of major procedures among the elderly. N Engl J Med, 2005 Aug 18; 353(7):683-91.

Liu Y, Berman P, Yip W, Liang H, Meng Q, Qu J, Li Z.  Health care in China: The role of non-government providers. Health Policy.  2005 Aug 19.

Rosenthal MB, Frank RG, Li Z, Epstein AM. Early experience with pay-for-performance: from concept to practice.  JAMA.  2005 Oct 12; 294(14):1788-93.  Was the No. 17th on the 25 most-viewed publications on The Commonwealth Fund Web site in 2005.

Jha AK, Orav EJ, Li Z, Epstein AM.  Concentration and quality of hospitals that care for elderly black patients.  Arch Intern Med. 2007 Jun 11; 167(11):1177-82.

Jha AK, Orav EJ, Li Z, Epstein AM.  The inverse relationship between mortality rates and performance in the hospital quality alliance measures.  Health Aff (Milwood). 2007 Jul-Aug; 26 (4):1104-10.

Gold J, Buonopane RJ, Caggiano RA, Picciotto M, Vogeli C, Kanner NT, Babcock RL, Li Z, Jellinek M, Drubner SJ, Murphy JM.  Assessing Outcomes in Child Psychiatry.  Am J Manag Care. 2009 Apr; 15 (4): 210-6.

DesRoches C, Donelan K, Buerhaus P, Li Z. Registered Nurses’ Use of Electronic Health Records: Findings from a National Survey, Medscape J Med. 2008; 10(7): 164.

Rosenthal MB, Li Z, Robertson A, Milstein A. Impact of Financial Incentives for Prenatal Care on Birth Outcomes and Spending.  Health Serv Res. 2009 Oct; 44 (5 Pt 1): 1465-79.  Epub 2009 Jul 13.

Simon NM, Herlands NH, Marks EH, Mancini C, Letamendi A., Li Z, Pollack MH, Ameringen MV, Stein MB. Childhood Maltreatment Linked to Greater Symptom Severity and Poorer Quality of Life and Function in Social Anxiety Disorder. Depress Anxiety. 2009; 26 (11): 1027-32.

Li Z, Hicks MH Measuring Depression in Chinese American Women: Validity of the CES-D. Psychiatry Res. 2010 Feb 28; 175 (3): 227-32.  Epub 2009 Dec 14.

Rosenthal MB, Li Z, Milstein A. Do Patients Continue to See Physicians Who Are Removed From a PPO Network? Am J Manag Care. 2009 Oct; 15 (10): 713-9.

Chien A, Li Z, Rosenthal MB. Improving Timely Childhood Immunizations through Pay for Performance in Medicaid Managed Care.  Health Serv Res. 2010 Sep 17.

Rosenthal MB, Schneider E., Friedberg M, Singer SJ, Eastman D, Li Z. Impact of the Rhode Island Multi-Payer Patient-Centered Medical Home Pilot on Health Care Utilization and Quality.  JAMA Internal Medicine. 2014 Nov; 173 (20).

Chien A, Eastman D, Li Z, Rosenthal MB. Impact of a Pay for Performance Program to Improve Diabetes Care in the Safety Net. Preventive Medicine. 11/2012; 55 Suppl: S80-5

Kinney GL, Thomas DSK, Cicutto L, Newman LS, Lutz S, Hokanson JE. (2014) The Protective Effect of Hispanic Ethnicity on Chronic Obstructive Pulmonary Disease Mortality is Mitigated by Smoking Behavior. Journal of Pulmonary and Respiratory Medicine. 4(6):220.

McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi P, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PMA, Celli B, Crim C, Rennard S, Wouters E, Bakke P, Tal-Singer R, Miller BE, Gulsvik A, Casaburi R, Wells JM, Regan EA, Make BJ, Hokanson JE, Lange C, Crapo JD, Beaty TH, Silverman EK, Hersh CP (2014) Common Genetic Variants Associated with Resting Oxygenation in Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Bio. 51(5):678-87.

Hersh CP, Make BJ, Lynch DA, Barr RG, Bowler RP, Calverley PM, Castaldi PJ, Cho MH, Coxson HO, DeMeo DL, Foreman MG, Han MK, Harshfield BJ, Hokanson JE, Lutz S, Ramsdell JW, Regan EA, Rennard SI, Schroeder JD, Sciurba FC, Steiner RM, Tal-Singer R, van Beek EJ, Silverman EK, Crapo JD; the COPDGene and ECLIPSE Investigators. (2014) Non-Emphysematous Chronic Obstructive Pulmonary Disease is Associated with Diabetes Mellitus. BMC Pulm Med. 14(1):164.

Marchetti N, Garshick E, Kinney GL, McKenzie A, Stinson D, Lutz SM, Lynch DA, Criner GJ, Silverman EK, Crapo JD, the COPDGene Investigators (2014) Association Between Occupational Exposure and Lung Function, Respiratory Symptoms and High Resolution CT Imaging in COPDGene. Am J Respir Crit Care Med. 190(7):756-62.

Lutz SM, Hokanson JE. (2014) Genetic Influences of Smoking and Clinical Disease: Understanding Behavioral and Biological Pathways with Mediation Analyses. Annals of Thoracic Medicine. 11(7):1082-1083.

Lutz SM, Hokanson JE, Lange C. (2014) An Alternative Hypothesis Testing Strategy for Secondary Phenotype Data in Case-Control Genetic Association Studies. Frontiers in Genetics. 5 (188).

McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Regan E, Eckbo E, Muralidhar N, Come CE, Cho M, Hersh CP, Lange C, Wouters, E, Coxson H, MacNee B, Rennard S, Lomas D, Agusti A, Celli B, Black-Shinn JL,Kinney GL, Lutz SM, Hokanson JE, Silverman EK and Washko GR. (2014) Quantitative CT Measures of Pectoralis Muscle Area and Disease Severity in COPD: a Cross-Sectional Study. Annals American Thoracic Society. 11(3):326-34.

Hughes G, Cruickshank-Quinn C, Reisdorph R, Lutz S, Reisdorph N, Bowler R, Kechris K. (2014) MSProcess: Summarization, Normalization, and Diagnostics for Processing of Mass Spectrometry Based Metabolomic Data. Bioinformatics. 30(1):133-134.

Lutz SM, Vansteelandt S, Lange C. (2013) Testing for Direct Genetic Effects Using a Screening Step in Family-Based Association Studies. Frontiers in Genetics. 4 (243).

Bowler R, Bahr T, Hughes G, Lutz S, Kim YI, Coldren C, Reisdroph N, Kechris K (2013) Integrative Omics Approach Identifies Interleukin 16 as a Biomarker of Emphysema. OMICS: A Journal of Integrative Biology. 17(12).

Lutz SM, Hokanson JE, Sharma S, Weiss S, Raby B, Lange C. (2013) On the Integration of Expression Profiles and Endo-Phenotypes in Genetic Association Studies: A Bayesian Approach to Determine the Path from Gene to Disease. Open Journal of Genetics. 3(3).

Hersh CP, Washko GR, Estepar RSJ, Lutz S, Friedman PJ, Han MK, Hokanson JE, Judy PF, Lynch DA, Make BJ, Marchetti N, Newell JD, Sciurba FC, Crapo JD, Silverman EK (2013) Paired Inspiratory-Expiratory Chest CT Scans to Assess for Small Airways Disease in COPD. Respiratory Research. 14(42). Aschard H, Lutz SM, Maus B, Duell EJ, Fingerlin T, Chatterjee N, Kraft P, Van Steen K. (2012) Challenges and Opportunities in Genome-Wide Environmental Interaction (GWEI) studies. Human Genetics. 131(10): 1591-613.