CHeRP News Archive: 2022

CHeRP News Archive: 2022

December

Hadley Stevens Smith and colleagues article “Access to clinically indicated genetic tests for pediatric patients with Medicaid: Evidence from outpatient genetics clinics in Texas” was published in Genetics in Medicine.

Hadley Stevens Smith’s article “Lessons learned while starting multi-institutional genetics research in diverse populations: A report from the Clinical Sequencing Evidence-Generating Research (CSER) consortium” is featured in Contemporary Clinical Trials!

Kurt Christensen’s publication “Parents' decision-making regarding whether to receive adult-onset only genetic findings for their children: Findings from the BabySeq Project” was published in Genetics in Medicine!

Katherine Yih and Judy Maro’s publication “A broad assessment of covid-19 vaccine safety using tree-based data-mining in the vaccine safety datalink” is featured in Vaccine!

CHeRP had their Annual Secret Snowflake Lunch!

CHeRP held a lunch to celebrate Alison Galbraith and all of her work as a member of CHeRP!

November

Congratulations to Alison Galbraith (pictured at left) and Davene Wright for participating in the Point32 Health-Institute Symposium!

Katherine Yih’s article “Kawasaki Disease Following the 13-valent Pneumococcal Conjugate Vaccine and Rotavirus Vaccines” is featured in Pediatrics.

Davene Wright and colleagues’ article “Student-Athlete Preferences for Sexual Violence Reporting: A Discrete Choice Experiment” is featured in Patient!

Sharon Lutz and colleagues’ publication “Increased chest CT derived bone and muscle measures capture markers of improved morbidity and mortality in COPD” is featured in Respiratory Research!

Sharon Lutz, Kirsten Voorhies and colleagues publication “A robust and adaptive framework for interaction testing in quantitative traits between multiple genetic loci and exposure variables” is featured in PLoS Genetics.

Kurt Christensen’s article “Workforce Considerations When Building a Precision Medicine Program” was published in the Journal of Personalized Medicine.

Kurt Christensen’s article “Awareness and utilization of genetic testing among Hispanic and Latino adults living in the US: The Hispanic Community Health Study/Study of Latinos” was published in HGG Advances.

Hadley Stevens Smith’s article “Key drivers of family-level utility of pediatric genomic sequencing: a qualitative analysis to support preference research” was published in the European Journal of Human Genetics.

October

Katherine Yih and colleagues’ paper “Active Post-Licensure Safety Surveillance for Recombinant Zoster Vaccine Using Electronic Health Record Data” was published in the American Journal of Epidemiology.

Katherine Yih and colleagues’ paper “Sequential Data-Mining for Adverse Events after Recombinant Herpes Zoster Vaccination Using the Tree-Based Scan Statistic” is published in the American Journal of Epidemiology.

Ann Wu was one of the theme coordinators for the October issue of The Journal of Allergy and Clinical Immunology: In Practice. October 2022’s theme was Telemedicine 2022.

Ann Wu and colleagues’ article “Could Telemedicine Be Here to Stay? Understanding the Rapidly Changing Landscape of Telemedicine in Allergy and Immunology Practice” was published in The Journal of Allergy and Clinical Immunology: In Practice.

Sharon Lutz and colleagues’ article “FGF20 and PGM2 variants are associated with childhood asthma in family-based whole-genome sequencing studies” was published in Human Molecular Genetics.

In October CHeRP hosted Natasha Bonhomme- Chief Strategy Officer, Genetic Alliance as our October CHeRP seminar. Natasha presented “What the Future of Genomics Can Learn From 60 years of Newborn Screening”.

CHeRP meet at Lookout Farm in Natick, MA for their Fall Outing in October! The day was spent Apple picking, lunch at the farm, and cider tasting!

September

Ann Chen Wu and colleagues’ article “Teleallergy: Where Have We Been and Where Are We Going?” is published in the Journal of Allergy and Clinical Immunology: In Practice.

Ann Chen Wu and colleagues’ article “Housing Instability and Homelessness—An Undertreated Pediatric Chronic Condition” is published in JAMA Pediatrics.

Alon Peltz and colleagues’ article “Measuring health disparities using a continuous social risk factor” is published in Health Services Research.

Davene Wright and colleagues’ article “Cost-Effectiveness of 5 Public Health Approaches to Prevent Eating Disorders” is published in American Journal of Preventive Medicine.

August

CHeRP welcomes our newest faculty member Dr. Hadley Stevens Smith! Dr. Smith is a health economist and scholar in the ethical, legal, and social implications (ELSI) of genomics. Dr. Smith develops approaches to integrate and advance health economic and ELSI research in genomics. Dr. Smith comes from Baylor college of Medicine, where she was a Health Policy Fellow in the Center for Medical Ethics and Health Policy. Welcome Dr. Smith!

CHeRP welcomes our newest research fellow Natalie Riva Smith, PhD! Natalie joins CHeRP as a postdoctoral research fellow working with Davene Wright. Natalie’s main research interest is to promote the implementation of evidence-informed policies to prevent cancer and chronic disease. To that end, she pursues research geared towards (1) using decision support methods, mainly simulation modeling, to assess the comparative health and economic effects of public health policies, and (2) improving how researchers disseminate findings from simulation modeling studies to policymakers. She earned her PhD in Health Policy and Management and her MS in Biostatistics from UNC Chapel Hill.

July

Davene Wright presented “InvesT1D: Improving adolescent diabetes health at what cost?” at a seminar hosted by Kaiser Permanente Washington.

Ann Wu, Pamela McMahon, and colleagues’ article “Use of Mepolizumab in Children and Adolescents with Asthma in the USA” is published in Journal of Respiration.

Alon Peltz, Madison Hickingbotham, Ann Wu, and colleagues’ article “The Role of Social Determinants of Health in the Use of Telemedicine for Asthma in Children” is published in The Journal of Allergy and Clinical Immunology: In Practice.

Alison Galbraith and members of The Asthma CHECC (Clinics Helping Expand Cost Conversations) study put together this video on making asthma care more affordable! To watch the video, click here.

June

Alon Peltz and colleagues’ article “Analysis of Racial and Ethnic Diversity of Population Served and Imaging Used in US Children’s Hospital Emergency Departments” is published in JAMA Network Open.

Sharon Lutz and colleagues’ article “Machine Learning Prediction of Progression in Forced Expiratory Volume in 1 Second in the COPDGene® Study” is published in The Journal of the COPD Foundation.

Elena Faugno, Ann Wu, Alison Galbraith, and colleagues’ article “Leveraging Telemedicine to Reduce the Financial Burden of Asthma Care” is published in The Journal of Allergy and Clinical Immunology: In Practice.

Ann Wu, Alison Galbraith, and colleagues’ article “Reply to ‘When too much is too much’” is published in The Journal of Allergy and Clinical Immunology: In Practice.

May

Sharon Lutz, Joanne Sordillo, Ann Wu and colleagues’ article “Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma” is published in Thorax.

Sharon Lutz, Kirsten Voorhies, Ann Wu and colleagues’ article “Selection bias when inferring the effect direction in Mendelian randomization” is published in Genetic Epidemiology.

Kurt Christensen and colleagues’ article “Parental Attitudes Toward Standard Newborn Screening and Newborn Genomic Sequencing: Findings From the BabySeq Study” is published in Frontiers in Genetics.

Kirsten Voorhies, Ann Wu, Sharon Lutz, and colleagues’ article “Covariate adjustment of spirometric and smoking phenotypes: The potential of neural network models” is published in PLoS One.

For our May CHeRP Seminar we hosted Dr. Kyle Brothers, MD, PhD Chief Scientific Office for Norton Children’s Research Institute. Dr. Brothers presented “Utility of Genome Sequencing in Pediatric Neurodevelopment Conditions”.

Dr. Kyle Brothers, MD, PhD, May Seminar Guest Speaker.

April

Kurt Christensen and colleagues’ article “Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases” is published in JAMA Oncology.

Congratulations to Sharon Lutz on her receipt of an R01 funded study from The National Institute of Mental Health (NIMH) entitled “The role of sex in genetic association studies of depression.”

Congratulations to Claire Abraham for winning best oral presentation by a trainee at the Region 1 Academic Pediatric Association Conference at this year’s PAS Conference! Claire presented “Predictors of Influenza Vaccine Uptake among Children During the COVID-19 Pandemic.”

Claire Abraham presenting at PAS.

March

Davene Wright was featured in the March Newsletter for The Nutrition Obesity Research Center at Harvard. Click here for the full newsletter.

Alon Peltz and colleagues’ paper “Promoting Child Health Equity Through Medicaid Innovation” was published in Pediatric Annals.

Alon Peltz and colleagues’ paper “Supplemental Nutrition Assistance Program participation and health care expenditures in children” was published in BMC Pediatrics.

Ann Wu and colleagues’ paper “Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma” was published in Nature Medicine.

CHeRP hosted Dr. Lisa Prosser, PhD as our CHeRP Visiting Professor for this year! Dr. Prosser presented “Using Decision Sciences to Assess the Value of Vaccination Against COVID-19 in Children and Adults”. Thanks for coming Dr. Prosser!

February

Alon Peltz and colleagues’ paper “Variation in Condition-Specific Readmission Rates Across US Children's Hospitals” is published in Academic Pediatrics.

Ann Wu and colleagues’ paper “Genetic associations and architecture of asthma-chronic obstructive pulmonary disease overlap” is published in CHEST.

Katherine Yih and colleagues’ paper “A Broad Safety Assessment of the Recombinant Herpes Zoster Vaccine” is published in American Journal of Epidemiology.

Sharon Lutz, Kirsten Voorhies, Ann Wu, and colleagues’ article “The influence of unmeasured confounding on the MR Steiger approach” is published in Genetic Epidemiology.

CHeRP hosted Dr. Charlene Wong for a February seminar.

January

CHeRP Member Alon Peltz and colleagues’ article “Clinical and public policy interventions to address food insecurity among children” is published in Current Opinion in Pediatrics

CHeRP Members Alison Galbraith, Lauren Cripps, Mikaela Batista, and colleagues’ article “Strategies commercially-insured families use to manage the cost of asthma care: a qualitative interview study” is published in Journal of Asthma

CHeRP Member Alon Petlz and colleagues’ article “Variation in Condition-Specific Readmission Rates Across U.S. Children's Hospitals” is published in Academic Pediatrics

CHeRP Members Joanne Sordillo, Sharon Lutz, Ann Wu, and colleagues’ article “Pharmacogenetics of Bronchodilator Response: Future Directions” is published in Current Allergy and Asthma

CHeRP Members Mei-Sing, Joanne Sordillo, Ann Wu and colleagues’ article “Multiomics analysis identifies BIRC3 as a novel glucocorticoid response–associated gene” is published in The Journal of Allergy and Clinical Immunology

CHeRP Members Natalia Kunst, Kurt Christensen, Pamela McMahon, Ann Wu, and colleagues’ article “Population-Based Newborn Screening for Germline TP53 Variants: Clinical Benefits, Cost-Effectiveness, and Value of Further Research” is published in Journal of the National Cancer Institute

CHeRP Member Sharon Lutz and colleagues’ article “A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data” is published in Genes

CHeRP Members Chris Lu, Pamela McMahon, and Ann Wu’s article “Modeling Genomic Screening in Newborns” is published in JAMA Pediatrics.

CHeRP hosted Dr. Beth A. Tarini for our January CHeRP Seminar.